Recruited at a young age by the Australian Institute of Sports, he’s part of the Under 16, Under 18 and Under 20 regional teams for the state of Victoria in the mid 90’s. 

His debut in Australia’s NBL (Australia’s highest league) comes in the 1998/1999 championship with the Wollongong Hawks and good performances earn David Andersen interest from NBA scouts as well as from some European clubs. In the summer of 1999, he signs with Virtus Bologna. During his four years there, rich in prestigious wins (Euroleague, national title and Coppa Italia in 2001, the latter repeated in 2002), Andersen receives a call from the Atlanta Hawks, who add him to the 2002 draft at number 37. However, he doesn’t go to the NBA and remains with Virtus Bologna for another season. The following summer, Andersen gets signed by Mens Sana Basket, with whom he wins the 2003/2004 national title and plays Euroleague’s Final Four in Tel Aviv. Such an extraordinary end to the season makes him quite appetizing to the European market, and he switches to CSKA Moscow the summer of 2004. His adventure in Russia lasts four seasons, during which he affirms himself as one of the old continent’s best centers and contributes to his team’s Euroleague wins the 2005/06 and 2007/08 seasons, as well as to several other national titles. The summer of 2008, he’s signed by Barcelona, where he plays only one season before beginning the following season in Houston, where he remains one year. He then heads to Toronto for a few months at the start of 2010/11, then moves to the New Orleans Hornets in November, his least team before returning to Siena.The 2011/2012 season starts off with the win of the Italian Supercup